Effects of spirulina supplementation on selected anthropometric, biochemical, and hematological parameters of HIV-infected adults in Ouagadougou, Burkina Faso.


HENRI GAUTIER OUEDRAOGO, SENI KOUANDA, FABRICE BATIONO, BOUKARÉ DOULOUGOU, LAETITIA OUEDRAOGO/NIKIEMA, HERMAN LANOU, SIMON TIENDREBEOGO, ARNAUD GUY KONSEIMBO, BENJAMIN LIESTMAN, JACQUES SIMPORE, JEAN-BAPTISTE NIKIEMA AND BLAISE SONDO.


Int. J. Biol. Chem. Sci. 7(2) : 607-617, April 2013. ISSN 1991-8631


http://ajol.info/index.php/ijbcs ;


http://indexmedicus.afro.who.int




ABSTRACT
The objective of the study was to assess the impact of spirulina supplementation on selected anthropometric, biochemical, and hematological parameters of HIV-infected adults in Ouagadougou. This quasi-experimental two-arm pilot study was conducted with adults infected with HIV-1 in Ouagadougou, Burkina Faso. A group of 50 participants received a 10 gram daily spirulina supplementation in addition to antiretroviral treatment (ART) while a 50 participant control group received only ART. At 9 months of followup, the mean values of mid-upper arm circumference (MUAC) and hemoglobin were significantly higher and creatinemia was lower in participants assigned to spirulina supplementation compared to those in the control group (p = 0.007, 0.002, and 0.01 respectively). At 6 months of follow-up, a significant decrease in gammaglobulins was observed in the intervention group as compared to the control group (p=0.04). There was no difference in the mean serum concentration of alanine transaminase (ALT) or amylasemia between the two groups.The daily 10 gram spirulina supplementation used in our study had a positive effect on several vital biological parameters in HIV-infected adults. Randomized clinical trials on large samples with longer followup periods will be necessary to test these assumptions.



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