Diallo JW, Sanfo O, Blot I, Meda N, Sawadogo P, Ouedraogo A, Simporé J.
J Fr Ophtalmol. 2009 Sep ;32(7):496-500. doi : 10.1016/j.jfo.2009.04.010. Epub 2009 Jun 10.
PMID : 19520457 [PubMed - indexed for MEDLINE]
INTRODUCTION : The frequency of sickle cell disease varies from 5% to 20% in Africa.
PATIENTS AND METHOD : This retrospective study investigated 173 patients in an ambulatory setting from August 2000 to July 2006. The study included 98 women and 75 men, aged 15-62 years, with a mean age of 26.7 years.
RESULTS : Only 89 patients (71 SC and 18 SS) were seen in ophthalmology, 44 (49%) had sickle cell retinopathy with 26 (29%) cases nonproliferative and 18 cases proliferative (20%). Among the 71 SC patients, 35 (50%) had sickle cell retinopathy, with 40% the proliferative form. Of the 18 SS patients, nine had a retinopathy (50%), with four cases proliferative.
DISCUSSION : Retinopathy is a frequent complication of sickle cell disease, which can lead to blindness, and its management better accessibility to the ophthalmologic examination and preventive treatment by laser photo coagulation.